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PYFAESTHETIC Becomes a Pioneer in Indonesia: Introducing an Innovative Combination of Methyl Aminolevulinate HCl and Panax Ginseng Callus Culture Extract for Optimal Skin Health

Jakarta, June 13, 2025 — Maintaining skin health is not just about appearance; it is also essential for preserving the skin’s natural protective function against external aggressors such as pollution, UV rays, and environmental stress. One of the most crucial aspects of skincare is maintaining skin hydration. Well-hydrated skin is better at functioning as a barrier, supporting regeneration, and preventing various skin problems such as irritation, dryness, and acne.

Medically, acne can be caused by several factors, including overly dry skin, excessive sebum (natural skin oil) production, clogged pores, the growth of Cutibacterium acnes bacteria, and inflammation. A combination of these factors can lead to skin lesions such as comedones, papules, pustules, and nodules.

In response to these needs, PT Pyridam Farma Tbk (PYFAGROUP), through its business unit PYFAESTHETIC, introduces an innovative solution combining two superior active ingredients: Methyl Aminolevulinate HCl (Methyl ALA) and Panax Ginseng Callus Culture Extract. This combination has been proven to optimally hydrate the skin, maintain skin health, and prepare the skin to receive subsequent treatments. These effects are enhanced when used together with a cleanser containing Sodium Hyaluronate, which helps retain moisture, reduce excess oil, and support acne prevention.

Methyl Aminolevulinate HCl is a lipophilic agent derived from 5-Aminolevulinic Acid (ALA). This active ingredient has better stability than ALA and high absorption capability, allowing for optimal skin penetration and maximum results. Meanwhile, Panax Ginseng Callus Culture Extract is a biotechnology-based active derived from the ginseng herbal plant, playing a role in protecting and maintaining the appearance of healthy skin.

“In several clinical studies, Methyl Aminolevulinate HCl has shown significant functions and mechanisms for supporting skin health, one of which is hydration, while Panax Ginseng Callus Culture Extract is believed to help maintain and protect the skin barrier, including soothing acne symptoms. Therefore, by combining these two active ingredients with their respective mechanisms, they can effectively support skin hydration and skin preparation for further treatments,” said Dr. Carlinda Nekawaty, Medical Expert of PYFAGROUP.

The combination of these two key active ingredients has been incorporated into a skin preparation routine. PYFAESTHETIC is committed to developing innovative products for the advancement of the aesthetic field in Indonesia, becoming the first to introduce the combination of Methyl Aminolevulinate HCl and Panax Ginseng Callus Culture Extract through the product RIBESKIN Dr. MAL. This product is part of a comprehensive skincare range designed to provide effective solutions for various skin concerns.

RIBESKIN Dr. MAL is designed to help hydrate the skin and act as a skin preparation agent, thereby helping control excess oil—a key step in preparing the skin before undergoing aesthetic procedures. With better skin hydration, the results of aesthetic treatments will be more optimal. This approach is highly suitable for various skin types, including oily and acne-prone skin.

One user of RIBESKIN Dr. MAL shared her experience: “After getting the Acne Clear Pro Facial treatment, my acne immediately healed, my skin became smoother, more hydrated, and brighter. You absolutely have to try this treatment!” said Yeni Setyani.

RIBESKIN Dr. MAL is now available at various beauty clinics across Indonesia as part of the skincare and skin preparation (pre-treatment) protocol. With a science-based approach and modern dermatological formulation, the use of Methyl Aminolevulinate HCl and Panax Ginseng Callus Culture Extract offers a new and effective alternative to support skincare—even for acne-prone skin—so it appears cleaner, healthier, and well-maintained.

About PYFAGROUP

PT Pyridam Farma Tbk (“PYFA”), known by the brand PYFAGROUP, is a public pharmaceutical company listed on the Indonesia Stock Exchange (Ticker: PYFA). PYFA operates business units producing prescription drugs in various forms such as tablets, capsules, creams, and injections. PYFA is the controlling shareholder of several subsidiaries, including PT Holi Pharma (based in Cimahi, West Java), PT Ethica Industri Farmasi (based in Cikarang, West Java), and Probiotec Pty Ltd (based in Australia).

About PYFAESTHETIC

PYFAESTHETIC is a business unit of PYFA focused on dermatology and aesthetics, offering a range of international aesthetic products registered with BPOM and the Ministry of Health, including skincare, fillers, and beauty devices for professional practitioners. In addition to product distribution, PYFAESTHETIC actively conducts professional training, including cadaver training abroad. With its commitment to quality, education, and collaboration, PYFAESTHETIC serves as a strategic partner for global aesthetic brands to enter the Indonesian market and support the development of the aesthetic industry in Southeast Asia.

Media Contact:

Leilanie Nadia Kusuma
Website: www.pyfa.co.id
Email: corcomm@pyfa.co.id

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